Jaguga, Florence; Turissini, Matthew; Kamaru Kwobah, Edith; Apondi, Edith; A. Enane, Leslie; Barasa, Julius; Kosgei, Gilliane; Olando, Yvonne; A. Ott, Mary; Kimaina, Allan; C. Aalsma, Matthew(PLOS.ONE, 2026-03-16)
Background
Youth in sub-Saharan Africa are at high risk of substance use yet lack access to
appropriate interventions. The goal of this project was to evaluate the feasibility of a
definitive trial to explore efficacy ...
Amubuomombe, Poli Philippe; Itsura, Peter; K Tonui, Philiph; Omenge Orang’o, Elkanah; Elly Odongo, Benjamin; Joseph Loehrer, Patrick; Cu-Uvin, Susan(BMJ, 2026-01-26)
Objective The standard treatment for high-grade
squamous intraepithelial lesions is excisional involving
the uterine cervix, while surveillance is an acceptable
approach for low-grade squamous intraepithelial lesions.
There ...
Oyungu, Eren; Keehn, Brandon; S McHenry, Megan; O Monahan, Patrick; M Joseph, Robert; Yoon, Seung-Yeol; G Carlucci, James; Saina, Chelagat; Khaitan, Alka; Baliddawa, Joice; McNally Keehn, Rebecca(BMJ, 2026-03-05)
Introduction The over 14 million African children who
are HIV-exposed but uninfected (CHEU) are at risk for poor
health outcomes, including neurodevelopmental conditions
such as autism; however, no study to date has ...
Background: To design accessible interventions, understanding how best to implement them in context is essential.
Strategies that reflect community perspectives may be most relevant and impactful. This study aimed to ...
ntroduction Each year, an estimated 1700 children should
be diagnosed with cancer in western Kenya, with leukaemia
making up nearly one-third of cases. However, far fewer are
actually diagnosed, highlighting significant ...
Background: Inclusion of youth (10-24 years) living with HIV (YLWH) in clinical
research is critical to addressing their unique vulnerabilities and improving care
outcomes. Examining the role of trust and relationship ...
Lotodo, Teresa; Melly, Beatrice; Wanjiku, Christopher M.; Kilachi, Caroline; Omondi, Austin; Kipkulei, Japheth(Scientific Research Publishing Inc., 2020-12-22)
Introduction: Bone marrow aspiration and biopsies are carried out princi-
pally to permit cytological assessment of marrow. The procedure is also indi-
cated for immunophenotypic, cytogenetic, molecular and other ...
Klootwijk, Larissa; Osamong, Lilian Apadet; Kimaiyo, Sally; Vik, Terry A.; van de Vijver, Steven; Kaspers, Gertjan; Njuguna, Festus(BMC, 2025-11-19)
Introduction Children in low- and middle-income countries face barriers to timely access to cancer care. Between
January and June 2023, an awareness campaign in Bungoma County, Kenya, aimed to address this issue. This ...
Addressing homelessness is a critical component of HIV prevention; in high income
countries, unconditional cash-transfer (CT) programs have been implemented for
housing support with youth populations. Here we describe a ...
ntroduction: Biobanking is common in research involving young people
living with HIV (YPLHIV). The ethics and policies guiding this practice
require careful consideration, especially given the population’s multiple
vu ...
Ouma, Gabriel Eliazaro; Omwod, Kimbley Asaso; Itsura, Peter; Poli, Philippe Amubuomombe; Wahome, Kanguru; Otieno, Odhiambo; Chiriswa, Nasengo; Jose, Green Harris; Awuor, Adagi; Rosen, Barry; Covens, Allan; Tonu, Philip(BMC, 2026-02-16)
Background: Adjuvant concurrent chemoradiotherapy following radical
hysterectomy is the cornerstone of curative-intent treatment for early-stage
cervical cancer. However, among people living with Human
Immunodeficiency ...
Background: Despite the introduction of single-pill antiretroviral therapy (ART), adherence remains suboptimal in
Sub-Saharan Africa. The Harambee study evaluated the effects of delivering integrated community-based (ICB) ...
Kisilu, Nicholas; Ndiwa, Dan; Tabu, Simiyu(International Surgery Journal, 2024-07)
Background: Mechanical intestinal obstruction (IO)c due to neoplasms is associated with high morbidity and
mortality rates worldwide. High rates of advanced stage cancers upon presentation in a resource-limited settings ...
Langat, Sandra; Njuguna, Festus; Kigen, Nicholas; Kipngetich, Martha; Olbara, Gilbert; Moormann, Ann; Vance, Gail H; Lotodo, Teresa; Odwar, Boaz; Loehrer, Patrick J.; Kaspers, Gertjan; Mostert, Saskia; Vik, Terry A.(American Society of Clinical Oncology, 2026-02-11)
PURPOSE Low survival rates among children with Burkitt lymphoma (BL) in low- and
middle-income countries (LMICs) are caused by multiple factors, including
delays in diagnosis and treatment abandonment. These issues are ...
Background Social and economic factors have considerable influence on the lives of people living with HIV (PLHIV).
These factors shape their health behaviors, willingness to engage with other members of their communities ...
Naanyu, Violet; Okwaro, Ferdinand; Ingrid Gicher; Mandeep Sura; Prachi Singh; Berhaun Fesshaye(PLOS GLOBAL PUBLIC HEALTH, 2026-01-06)
The COVID-19 pandemic significantly disrupted societies worldwide, and COVID-19
vaccination has been identified as instrumental in the fight against the pandemic.
While studies have examined uptake of COVID-19 vaccination, ...
Background: Youth living with HIV with perinatal infection spend a lifetime taking antiretroviral treatment (ART) to suppress
the virus, and face significant challenges to successfully maintaining ART adherence. Tools to ...
Background: children with perinatal HIV exposure are at increased risk for neurodevelopmental (ND) delays, yet
little is known about ND screening implementation for this population.
Methods: This longitudinal study ...
Hotels in Western Uganda continue to face survivability challenges arising from weak
succession planning structures and informal cultural practices that undermine
leadership continuity. This study examined how succession ...
Acute febrile illness (AFI) is a common cause of pediatric hospital visits in developing countries. Identifying the broad range of pathogens that can cause fever is critical to: improving AFI management, preventing unnecessary ...